Tuning is the final step, carried out only after most other setup and configuration is complete.
Rate and attitude controllers:
Autotune — Automates tuning PX4 rate and attitude controllers (recommended).
Automatic tuning works on frames that have reasonable authority and dynamics around all the body axes. It has primarily been tested on racing quads and X500, and is expected to be less effective on tricopters with a tiltable rotor.
Manual tuning using these guides are only needed if there is a problem with autotune:
MC Filter/Control Latency Tuning — Trade off control latency and noise filtering.